/* ═══════════════════════════════════════════════════
   OmicsLab — African Genomics Variant Atlas (Prompt 45)
   ═══════════════════════════════════════════════════ */

.va-wrap { display: flex; flex-direction: column; gap: 1.25rem; }

.va-hero {
  display: flex;
  align-items: flex-start;
  gap: 1rem;
  padding: 1.25rem;
  background: linear-gradient(135deg, rgba(63,185,80,.08), rgba(88,166,255,.05));
  border: 1px solid var(--border, #30363d);
  border-radius: .75rem;
}
.va-hero-icon { color: var(--accent, #3fb950); flex-shrink: 0; margin-top: .2rem; }
.va-hero-title { font-size: 1.15rem; font-weight: 700; color: var(--text-primary, #e6edf3); margin: 0 0 .35rem; }
.va-hero-sub   { font-size: .8rem; color: var(--text-secondary, #8b949e); margin: 0; line-height: 1.55; }

.va-controls {
  display: flex;
  align-items: center;
  gap: .75rem;
  flex-wrap: wrap;
}
.va-search-wrap {
  display: flex;
  align-items: center;
  gap: .5rem;
  background: var(--surface, #161b22);
  border: 1px solid var(--border, #30363d);
  border-radius: .5rem;
  padding: .4rem .75rem;
  color: var(--text-muted, #8b949e);
  flex: 1;
  min-width: 200px;
}
.va-search {
  background: none;
  border: none;
  outline: none;
  color: var(--text-primary, #e6edf3);
  font-size: .83rem;
  width: 100%;
}
.va-filter-chips { display: flex; gap: .4rem; flex-wrap: wrap; }
.va-chip {
  padding: .25rem .65rem;
  font-size: .7rem;
  border: 1px solid var(--border, #30363d);
  border-radius: 99px;
  background: none;
  color: var(--text-muted, #8b949e);
  cursor: pointer;
  transition: all .15s;
  white-space: nowrap;
}
.va-chip:hover { border-color: var(--accent, #3fb950); color: var(--accent, #3fb950); }
.va-chip.active { background: rgba(63,185,80,.12); border-color: var(--accent, #3fb950); color: var(--accent, #3fb950); font-weight: 600; }
.va-count { font-size: .72rem; color: var(--text-muted, #8b949e); white-space: nowrap; margin-left: auto; }

/* ── Table ── */
.va-table-wrap { overflow-x: auto; border-radius: .75rem; border: 1px solid var(--border, #30363d); }
.va-table { width: 100%; border-collapse: collapse; font-size: .8rem; }
.va-table thead { background: var(--surface-alt, #0d1117); }
.va-table th {
  padding: .65rem .9rem;
  text-align: left;
  font-size: .7rem;
  font-weight: 600;
  color: var(--text-muted, #8b949e);
  text-transform: uppercase;
  letter-spacing: .04em;
  border-bottom: 1px solid var(--border, #30363d);
  white-space: nowrap;
}
.va-sort { cursor: pointer; user-select: none; }
.va-sort:hover { color: var(--text-primary, #e6edf3); }
.va-sort--active { color: var(--accent, #3fb950); }

.va-row {
  border-bottom: 1px solid rgba(48,54,61,.5);
  cursor: pointer;
  transition: background .1s;
}
.va-row:hover { background: rgba(63,185,80,.04); }
.va-row td { padding: .6rem .9rem; vertical-align: top; }

.va-cell-id { min-width: 160px; }
.va-rsid    { font-weight: 600; color: var(--accent, #3fb950); font-family: 'JetBrains Mono', monospace; font-size: .75rem; }
.va-gene    { font-size: .7rem; color: var(--text-muted, #8b949e); margin-top: .15rem; }
.va-alleles { font-size: .68rem; color: var(--text-muted, #8b949e); font-family: 'JetBrains Mono', monospace; }

.va-disease { font-weight: 500; color: var(--text-primary, #e6edf3); font-size: .78rem; max-width: 200px; }

.va-acmg-badge {
  font-size: .67rem;
  font-weight: 700;
  padding: .15rem .45rem;
  border-radius: 4px;
  white-space: nowrap;
  letter-spacing: .01em;
}
.va-acmg-lg { font-size: .78rem; padding: .2rem .6rem; }

.va-cell-af { font-size: .82rem; color: var(--text-primary, #e6edf3); }
.va-af-global { color: var(--text-muted, #8b949e); }

/* ── Frequency bar ── */
.va-cell-bar { min-width: 120px; }
.va-bar-row  { display: flex; align-items: center; gap: .4rem; margin-bottom: .2rem; }
.va-bar-row:last-child { margin-bottom: 0; }
.va-bar-label { font-size: .58rem; color: var(--text-muted, #8b949e); width: 24px; flex-shrink: 0; }
.va-bar-track { flex: 1; height: 6px; background: var(--border, #30363d); border-radius: 3px; overflow: hidden; }
.va-bar-fill  { height: 100%; border-radius: 3px; transition: width .3s ease; }
.va-bar-africa { background: #3fb950; }
.va-bar-global { background: #58a6ff; }

.va-cell-action { white-space: nowrap; }
.va-analyze-btn { font-size: .7rem; display: flex; align-items: center; gap: .3rem; }

.va-empty { text-align: center; padding: 3rem; color: var(--text-muted, #8b949e); }
.va-empty-icon { display: flex; align-items: center; justify-content: center; margin-bottom: .75rem; opacity: .4; }

/* ── Detail panel ── */
.va-detail {
  background: var(--surface, #161b22);
  border: 1px solid var(--border, #30363d);
  border-radius: .75rem;
  padding: 1.25rem;
  position: relative;
  animation: va-slide-in .2s ease;
}
@keyframes va-slide-in { from { opacity:0; transform:translateY(8px); } to { opacity:1; transform:none; } }
.va-detail-close {
  position: absolute;
  top: .9rem;
  right: .9rem;
  background: none;
  border: none;
  color: var(--text-muted, #8b949e);
  cursor: pointer;
  display: flex;
  padding: .2rem;
}
.va-det-header { display: flex; align-items: flex-start; justify-content: space-between; gap: 1rem; margin-bottom: .5rem; }
.va-det-rsid   { font-family: 'JetBrains Mono', monospace; font-weight: 700; font-size: 1rem; color: var(--accent, #3fb950); }
.va-det-gene   { font-size: .75rem; color: var(--text-muted, #8b949e); margin-top: .2rem; }
.va-det-disease { font-weight: 600; font-size: .9rem; color: var(--text-primary, #e6edf3); margin-bottom: .6rem; }
.va-det-note   { font-size: .82rem; color: var(--text-secondary, #8b949e); line-height: 1.6; margin-bottom: 1rem; }

.va-det-af-grid { display: grid; grid-template-columns: repeat(3, 1fr); gap: .75rem; margin-bottom: 1rem; }
.va-det-af-box  { padding: .75rem; background: var(--surface-alt, #0d1117); border-radius: .5rem; text-align: center; }
.va-det-af-pct  { font-size: 1.4rem; font-weight: 800; }
.va-af-africa .va-det-af-pct { color: #3fb950; }
.va-af-global .va-det-af-pct { color: #58a6ff; }
.va-det-af-label { font-size: .65rem; color: var(--text-muted, #8b949e); text-transform: uppercase; letter-spacing: .04em; margin-top: .2rem; }
.va-det-actions { display: flex; gap: .75rem; flex-wrap: wrap; }

@media (max-width: 640px) {
  .va-table th:nth-child(5),
  .va-table td:nth-child(5) { display: none; }
  .va-det-af-grid { grid-template-columns: 1fr 1fr; }
}